Single-Atom Catalysts in Catalytic Biomedicine

doi:10.1002/adma.201905994

SIC OpenIR

	Single-Atom Catalysts in Catalytic Biomedicine
	Xiang, HJ; Feng, W; Chen, Y
	2020-02-01
Source Publication	ADVANCED MATERIALS
ISSN	0935-9648
Issue	8
Subtype	Article
Abstract	The intrinsic deficiencies of nanoparticle-initiated catalysis for biomedical applications promote the fast development of alternative versatile theranostic modalities. The catalytic performance and selectivity are the critical issues that are challenging to be augmented and optimized in biological conditions. Single-atom catalysts (SACs) featuring atomically dispersed single metal atoms have emerged as one of the most explored catalysts in biomedicine recently due to their preeminent catalytic activity and superior selectivity distinct from their nanosized counterparts. Herein, an overview of the pivotal significance of SACs and some underlying critical issues that need to be addressed is provided, with a specific focus on their versatile biomedical applications. Their fabrication strategies, surface engineering, and structural characterizations are discussed briefly. In particular, the catalytic performance of SACs in triggering some representative catalytic reactions for providing the fundamentals of biomedical use is discussed. A sequence of representative paradigms is summarized on the successful construction of SACs for varied biomedical applications (e.g., cancer treatment, wound disinfection, biosensing, and oxidative-stress cytoprotection) with an emphasis on uncovering the intrinsic catalytic mechanisms and understanding the underlying structure-performance relationships. Finally, opportunities and challenges faced in the future development of SACs-triggered catalysis for biomedical use are discussed and outlooked.
DOI	10.1002/adma.201905994
WOS Keyword	METAL-ORGANIC FRAMEWORKS ; PHOTODYNAMIC THERAPY ; MITOCHONDRIAL ROS ; OXIDATIVE STRESS ; OXYGEN ; CANCER ; SITES ; NANOPARTICLES ; NANOZYME ; DESIGN
Language	英语
WOS Research Area	Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
Publisher	WILEY-V C H VERLAG GMBH
Citation statistics
Document Type	期刊论文
Identifier	http://ir.sic.ac.cn/handle/331005/28378
Collection	中国科学院上海硅酸盐研究所
Recommended Citation GB/T 7714	Xiang, HJ,Feng, W,Chen, Y. Single-Atom Catalysts in Catalytic Biomedicine[J]. ADVANCED MATERIALS,2020(8).
APA	Xiang, HJ,Feng, W,&Chen, Y.(2020).Single-Atom Catalysts in Catalytic Biomedicine.ADVANCED MATERIALS(8).
MLA	Xiang, HJ,et al."Single-Atom Catalysts in Catalytic Biomedicine".ADVANCED MATERIALS .8(2020).

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