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Ultrasound-assisted synthesis of nanocrystallized silicocarnotite biomaterial with improved sinterability and osteogenic activity
Xu, SX; Wu, Q; Wu, J; Kou, HM; Zhu, YJ; Ning, CQ; Dai, KR
2020-04-21
Source PublicationJOURNAL OF MATERIALS CHEMISTRY B
ISSN2050-750X
Issue15Pages:3092
SubtypeArticle
AbstractIt has been proved that silicon-substituted calcium phosphate ceramics possess superior bone regeneration and resorbability to HA, while the synthesis of single-phase nanocrystallized high Si-containing calcium phosphate is still a challenge. In the present work, a novel and facile aqueous precipitation method assisted with ultrasonic irradiation was adopted firstly to synthesise a single-phase nanocrystallized calcium silicophosphate (Ca-5(PO4)(2)SiO4, CPS) biomaterial. Crystallization and morphology of Si-apatite precursors synthesized with or without ultrasonic assistance were primarily investigated and the related mechanism was discussed. Moreover, the sinterability, in vitro bioactivity and osteogenic activity of the synthesized CPS were studied in detail. Results showed that an ultrasonic cavitation effect could be beneficial to form a highly dispersive CPS precursor with a single Si-apatite phase, which greatly reduced the calcination temperature of CPS from 1350 degrees C to 1000 degrees C. Nanocrystallized CPS powders were obtained successfully under ultrasound-assisted conditions, which showed superior sinterability, in vitro bioactivity and osteogenic activity than those of micron-sized CPS and HA powders. It might be a promising candidate material for bone tissue regeneration applications.
DOI10.1039/c9tb02855b
WOS KeywordCALCIUM-PHOSPHATE BIOCERAMICS ; MECHANICAL-PROPERTIES ; HYDROXYAPATITE ; DIFFERENTIATION ; SILICON ; SCAFFOLDS ; REGENERATION ; REPAIR ; NANO ; SBF
Language英语
WOS Research AreaMaterials Science
PublisherROYAL SOC CHEMISTRY
Citation statistics
Cited Times:1[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.sic.ac.cn/handle/331005/28125
Collection中国科学院上海硅酸盐研究所
Recommended Citation
GB/T 7714
Xu, SX,Wu, Q,Wu, J,et al. Ultrasound-assisted synthesis of nanocrystallized silicocarnotite biomaterial with improved sinterability and osteogenic activity[J]. JOURNAL OF MATERIALS CHEMISTRY B,2020(15):3092.
APA Xu, SX.,Wu, Q.,Wu, J.,Kou, HM.,Zhu, YJ.,...&Dai, KR.(2020).Ultrasound-assisted synthesis of nanocrystallized silicocarnotite biomaterial with improved sinterability and osteogenic activity.JOURNAL OF MATERIALS CHEMISTRY B(15),3092.
MLA Xu, SX,et al."Ultrasound-assisted synthesis of nanocrystallized silicocarnotite biomaterial with improved sinterability and osteogenic activity".JOURNAL OF MATERIALS CHEMISTRY B .15(2020):3092.
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