KMS Shanghai Institute of Ceramics，Chinese Academy of Sciences
| AgFeS(2)nanoparticles as a novel photothermal platform for effective artery stenosis therapy | |
| Peng, X; Liu, JC; Ming, C; Li, B; Zhao, Z; Ye, KC; Zeng, M; Zou, RJ; Lu, XW; Hu, JQ | |
| 2020-05-28 | |
| Source Publication | NANOSCALE
 |
| ISSN | 2040-3364 |
| Issue | 20Pages:11288 |
| Subtype | Article |
| Abstract | Ternary I-III-VI(2)semiconductors usually have narrow band gaps and large absorption coefficients arising from the unique characteristics of their outer-d valence electrons, which are intimately connected with the photothermal conversion properties. AgFeS(2)is known as one such material that has the potential to absorb near-infrared light. In this work, we utilized density functional theory (DFT) calculations to evaluate the electronic structure and optical absorption properties of AgFeS2. Strong absorptions were predicted over a wide Vis-NIR region due to the localized 3d electron of Fe atoms, which agree quite well with the UV-Vis-NIR spectra measured by experiment. The as-prepared AgFeS(2)nanoparticles were then modified with mPEG-DSPE, an efficient photothermal agent for artery stenosis therapy. Its photothermal conversion effect has been systematically studied, indicating the potential for causing the hyperthermia of macrophages, an essential part of the artery inflammation response. More importantly, bothin vitrocell experiments andin vivomouse-model studies show that the induction of hyperthermia in artery stenosis by using AgFeS(2)nanoparticles is safe and effective when injected at a very low concentration. This study provides a novel photothermal platform derived from the inheritability of bandgap structure and also promotes the process of artery inflammation and stenosis therapy. |
| DOI | 10.1039/d0nr01587c |
| WOS Keyword | NANOCRYSTALS ; NANOCOMPOSITES ; TRANSFORMATION ; NANOPARTICLES ; NANOPLATFORM ; EFFICIENCY ; LIGHT ; LASER |
| Language | 英语 |
| WOS Research Area | Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics |
| Publisher | ROYAL SOC CHEMISTRY |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.sic.ac.cn/handle/331005/28040 |
| Collection | 中国科学院上海硅酸盐研究所 |
| Recommended Citation GB/T 7714 | Peng, X,Liu, JC,Ming, C,et al. AgFeS(2)nanoparticles as a novel photothermal platform for effective artery stenosis therapy[J]. NANOSCALE,2020(20):11288. |
| APA | Peng, X.,Liu, JC.,Ming, C.,Li, B.,Zhao, Z.,...&Hu, JQ.(2020).AgFeS(2)nanoparticles as a novel photothermal platform for effective artery stenosis therapy.NANOSCALE(20),11288. |
| MLA | Peng, X,et al."AgFeS(2)nanoparticles as a novel photothermal platform for effective artery stenosis therapy".NANOSCALE .20(2020):11288. |
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