KMS Shanghai Institute of Ceramics，Chinese Academy of Sciences
| Preparation of Zn doped mesoporous silica nanoparticles (Zn-MSNs) for the improvement of mechanical and antibacterial properties of dental resin composites | |
| Bai, XX; Lin, CC; Wang, YY; Ma, J; Wang, X; Yao, XH; Tang, B | |
| 2020-06-01 | |
| Source Publication | DENTAL MATERIALS
 |
| ISSN | 0109-5641 |
| Issue | 6Pages:794 |
| Subtype | Article |
| Abstract | Objective. The purpose of this work was to explore the enhancement effect of zinc doped mesoporous silica nanoparticles (Zn-MSNs), which could form micromechanical interlocking with resin matrix and sustainably release Zn2+, on the mechanical and antibacterial properties of the dental resin composites. Methods. Zn-MSNs were prepared by a sol-gel method, and characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM) and N-2 adsorption/desorption. The mechanical properties of the dental composites reinforced by Zn-MSNs were measured by a universal mechanical testing machine. Antibacterial activities of dental composites were evaluated by both qualitative and quantitative analysis using Streptococcus mutans (S. mutans). The cytotoxicity of the Zn-MSNs filled dental composites was investigated by osteoblasts (OBs). Results. The synthesized Zn-MSNs possessed good monodispersity with an average particle size of about 138 nm. The mechanical properties of the composites gradually increased with the increase of the content of Zn-MSNs. The flexural strength, flexural modulus, compressive strength and micro-hardness of the composites containing 15 wt% Zn-MSNs were 31.21%, 50.47%, 53.83% and 26.79% higher than the samples with no Zn-MSNs, respectively. The antibacterial performance was significantly improved by the addition of Zn-MSNs and the antibacterial rate of the composite with 15 wt% of Zn-MSNs reached 100%. Cytotoxicity tests revealed that all the composites were biocompatible during OBs incubation. Significance. The prepared Zn-MSNs can effectively improve the mechanical and antibacterial properties of the dental resin composites. (C) 2020 The Academy of Dental Materials. Published by Elsevier Inc. All rights reserved. |
| DOI | 10.1016/j.dental.2020.03.026 |
| WOS Keyword | CYTOCOMPATIBILITY ; SIZE ; CONVERSION ; SCAFFOLDS ; SILVER ; WEAR |
| Language | 英语 |
| WOS Research Area | Dentistry, Oral Surgery & Medicine ; Materials Science |
| Publisher | ELSEVIER SCI LTD |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.sic.ac.cn/handle/331005/28018 |
| Collection | 中国科学院上海硅酸盐研究所 |
| Recommended Citation GB/T 7714 | Bai, XX,Lin, CC,Wang, YY,et al. Preparation of Zn doped mesoporous silica nanoparticles (Zn-MSNs) for the improvement of mechanical and antibacterial properties of dental resin composites[J]. DENTAL MATERIALS,2020(6):794. |
| APA | Bai, XX.,Lin, CC.,Wang, YY.,Ma, J.,Wang, X.,...&Tang, B.(2020).Preparation of Zn doped mesoporous silica nanoparticles (Zn-MSNs) for the improvement of mechanical and antibacterial properties of dental resin composites.DENTAL MATERIALS(6),794. |
| MLA | Bai, XX,et al."Preparation of Zn doped mesoporous silica nanoparticles (Zn-MSNs) for the improvement of mechanical and antibacterial properties of dental resin composites".DENTAL MATERIALS .6(2020):794. |
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