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Advanced Theragenerative Biomaterials with Therapeutic and Regeneration Multifunctionality
Chen, BD; Xiang, HJ; Pan, SS; Yu, LD; Xu, TM; Chen, Y
2020-08-01
Source PublicationADVANCED FUNCTIONAL MATERIALS
ISSN1616-301X
Issue34
SubtypeArticle
AbstractAll tissues and organs can be affected by diseases, and treatments for these diseases can cause damage to surrounding healthy tissues and organs. Therefore, treatment is required that involves disease therapy alongside tissue/organ regeneration. The design, construction, and biomedical applications of biomaterial platforms with both disease-therapeutic and tissue-regeneration multifunctionalities are in demand, which are herein referred to as theragenerative (abbreviation of therapy and regeneration) biomaterials. Due to the rapid development of theragenerative biomaterials in versatile biomedical applications, this progress report aims to summarize, discuss, and highlight the rational construction of distinctive theragenerative biomaterials with intrinsic therapeutic performance and tissue-regeneration bioactivity. Based on the intrinsic response to either external physical triggers (e.g., photonic response or magnetic-field response) or endogenous disease microenvironments (e.g., mild acidity or overexpressed hydrogen peroxide) and tissue-regeneration bioactivity, these theragenerative biomaterials are extensively explored in various biomedical fields, including bone-tumor therapy/regeneration, bone antibacterial therapy/regeneration, skin-tumor therapy/regeneration, skin antibacterial therapy/regeneration, breast-tumor therapy/adipose-tissue regeneration, and osteoarticular-tuberculosis therapy/bone-tissue regeneration. The challenges faced and future developments of these distinctive theragenerative biomaterials are discussed, as are methods for further promoting their clinical translation.
DOI10.1002/adfm.202002621
WOS KeywordBIOACTIVE GLASS SCAFFOLDS ; IRON-OXIDE NANOPARTICLES ; HYDROGENATED BLACK TIO2 ; PHOTOTHERMAL THERAPY ; GRAPHENE OXIDE ; MAGNETIC NANOPARTICLES ; ANTIBACTERIAL ACTIVITY ; DRUG-DELIVERY ; BONE REGENERATION ; CANCER-THERAPY
Language英语
WOS Research AreaChemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
PublisherWILEY-V C H VERLAG GMBH
Citation statistics
Cited Times:1[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.sic.ac.cn/handle/331005/27949
Collection中国科学院上海硅酸盐研究所
Recommended Citation
GB/T 7714
Chen, BD,Xiang, HJ,Pan, SS,et al. Advanced Theragenerative Biomaterials with Therapeutic and Regeneration Multifunctionality[J]. ADVANCED FUNCTIONAL MATERIALS,2020(34).
APA Chen, BD,Xiang, HJ,Pan, SS,Yu, LD,Xu, TM,&Chen, Y.(2020).Advanced Theragenerative Biomaterials with Therapeutic and Regeneration Multifunctionality.ADVANCED FUNCTIONAL MATERIALS(34).
MLA Chen, BD,et al."Advanced Theragenerative Biomaterials with Therapeutic and Regeneration Multifunctionality".ADVANCED FUNCTIONAL MATERIALS .34(2020).
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