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Chemoreactive nanomedicine
Feng, W; Chen, Y
2020-08-21
Source PublicationJOURNAL OF MATERIALS CHEMISTRY B
ISSN2050-750X
Issue31Pages:6753
SubtypeArticle
AbstractTriggering specific chemical reactions in the disease microenvironment can produce species for disease treatment that have high theranostic performance and low side effects on healthy cells/tissues. Emerging chemoreactive nanomedicine employs nanotechnology to enable the occurrence and/or enhance the rate/efficiency ofin situchemical reactions to satisfy the strict requirements of versatile biomedical applications. This perspective discusses the four essential factors that play roles in the theranostic performance, including nanoreactants, nanoproducts, nanocatalysts and reaction conditions. The design and fabrication principles/strategies for diverse nanosystems and optimization methodologies for reaction conditions in chemoreactive nanomedicine are summarized and discussed alongside the most representative paradigms available. The explored versatile biomedical applications of chemoreactive nanomedicine are clarified, such as tumor therapy, bioimaging, tissue regeneration and antibacterial properties. Finally, this perspective clarifies the difficulties/challenges faced and provides an outlook detailing the future developments/prospects of this intriguing chemoreactive nanomedicine for future clinical translations.
DOI10.1039/d0tb00436g
WOS KeywordHOLLOW MESOPOROUS ORGANOSILICA ; SOLID TUMOR MICROENVIRONMENT ; HYDROGEN-PEROXIDE ; PHOTOTHERMAL THERAPY ; CERIA NANOPARTICLES ; TIO2 PHOTOCATALYSIS ; OXYGEN ; ENHANCE ; NANOTECHNOLOGY ; THERANOSTICS
Language英语
WOS Research AreaMaterials Science
PublisherROYAL SOC CHEMISTRY
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Document Type期刊论文
Identifierhttp://ir.sic.ac.cn/handle/331005/27817
Collection中国科学院上海硅酸盐研究所
Recommended Citation
GB/T 7714
Feng, W,Chen, Y. Chemoreactive nanomedicine[J]. JOURNAL OF MATERIALS CHEMISTRY B,2020(31):6753.
APA Feng, W,&Chen, Y.(2020).Chemoreactive nanomedicine.JOURNAL OF MATERIALS CHEMISTRY B(31),6753.
MLA Feng, W,et al."Chemoreactive nanomedicine".JOURNAL OF MATERIALS CHEMISTRY B .31(2020):6753.
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