SIC OpenIR
Bioactive Self-Pumping Composite Wound Dressings with Micropore Array Modified Janus Membrane for Enhanced Diabetic Wound Healing
Bao, F; Pei, G; Wu, ZC; Zhuang, H; Zhang, ZWB; Huan, ZG; Wu, CT; Chang, J
2020-12-01
Source PublicationADVANCED FUNCTIONAL MATERIALS
ISSN1616-301X
Issue49
SubtypeArticle
AbstractTreatment of chronic wounds such as diabetic wounds with large volumes of biofluids is a significant clinical challenge due to ischemia caused by localized edema. To alleviate edema and stimulate angiogenesis, a four-layer composite dressing is designed with a micropore array modified Janus membrane for self-pumping and bioactive ion backflow, a superabsorbent layer for high capacity water absorption, and a bioactive layer containing bioglass for stimulating angiogenesis. The modified Janus membrane not only allows wound exudates transport from wound bed to the dressing, but also enables controlled backflow of bioactive ion containing fluid to the wound bed for stimulating angiogenesis. The in vivo experiment confirms the function of composite dressing in reducing wound edema, stimulating blood vessel formation and promoting diabetic wound healing. These results demonstrate that the novel composite dressing is a promising wound healing biomaterial for promoting chronic wound healing, and the unique characteristics of the micropore arrayed Janus membrane may extend its applications in biomedicine.
DOI10.1002/adfm.202005422
WOS KeywordTHERAPY
Language英语
WOS Research AreaChemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
PublisherWILEY-V C H VERLAG GMBH
Citation statistics
Document Type期刊论文
Identifierhttp://ir.sic.ac.cn/handle/331005/27764
Collection中国科学院上海硅酸盐研究所
Recommended Citation
GB/T 7714
Bao, F,Pei, G,Wu, ZC,et al. Bioactive Self-Pumping Composite Wound Dressings with Micropore Array Modified Janus Membrane for Enhanced Diabetic Wound Healing[J]. ADVANCED FUNCTIONAL MATERIALS,2020(49).
APA Bao, F.,Pei, G.,Wu, ZC.,Zhuang, H.,Zhang, ZWB.,...&Chang, J.(2020).Bioactive Self-Pumping Composite Wound Dressings with Micropore Array Modified Janus Membrane for Enhanced Diabetic Wound Healing.ADVANCED FUNCTIONAL MATERIALS(49).
MLA Bao, F,et al."Bioactive Self-Pumping Composite Wound Dressings with Micropore Array Modified Janus Membrane for Enhanced Diabetic Wound Healing".ADVANCED FUNCTIONAL MATERIALS .49(2020).
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Bao, F]'s Articles
[Pei, G]'s Articles
[Wu, ZC]'s Articles
Baidu academic
Similar articles in Baidu academic
[Bao, F]'s Articles
[Pei, G]'s Articles
[Wu, ZC]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Bao, F]'s Articles
[Pei, G]'s Articles
[Wu, ZC]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.