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A materials-science perspective on tackling COVID-19
Tang, ZM; Kong, N; Zhang, XC; Liu, Y; Hu, P; Mou, S; Liljestrom, P; Shi, JL; Tan, WH; Kim, JS; Cao, YH; Langer, R; Leong, KW; Farokhzad, OC; Tao, W
2020-10-14
Source PublicationNATURE REVIEWS MATERIALS
ISSN2058-8437
Issue11Pages:847
SubtypeReview
AbstractMaterials science provides tools and technologies for the protection against viral infections, as well as for the understanding, diagnosis, treatment and prevention of viral diseases. This Review discusses present and future directions in antiviral materials-science research, with a focus on COVID-19. The ongoing SARS-CoV-2 pandemic highlights the importance of materials science in providing tools and technologies for antiviral research and treatment development. In this Review, we discuss previous efforts in materials science in developing imaging systems and microfluidic devices for the in-depth and real-time investigation of viral structures and transmission, as well as material platforms for the detection of viruses and the delivery of antiviral drugs and vaccines. We highlight the contribution of materials science to the manufacturing of personal protective equipment and to the design of simple, accurate and low-cost virus-detection devices. We then investigate future possibilities of materials science in antiviral research and treatment development, examining the role of materials in antiviral-drug design, including the importance of synthetic material platforms for organoids and organs-on-a-chip, in drug delivery and vaccination, and for the production of medical equipment. Materials-science-based technologies not only contribute to the ongoing SARS-CoV-2 research efforts but can also provide platforms and tools for the understanding, protection, detection and treatment of future viral diseases.
DOI10.1038/s41578-020-00247-y
WOS KeywordMESSENGER-RNA VACCINES ; ZIKA VIRUS-INFECTION ; LABELED RABIES-VIRUS ; GENE-EXPRESSION ; CYTOKINE STORM ; INFLUENZA ; DELIVERY ; DNA ; NANOPARTICLES ; TRANSMISSION
Language英语
WOS Research AreaScience & Technology - Other Topics ; Materials Science
PublisherNATURE RESEARCH
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Document Type期刊论文
Identifierhttp://ir.sic.ac.cn/handle/331005/27691
Collection中国科学院上海硅酸盐研究所
Recommended Citation
GB/T 7714
Tang, ZM,Kong, N,Zhang, XC,et al. A materials-science perspective on tackling COVID-19[J]. NATURE REVIEWS MATERIALS,2020(11):847.
APA Tang, ZM.,Kong, N.,Zhang, XC.,Liu, Y.,Hu, P.,...&Tao, W.(2020).A materials-science perspective on tackling COVID-19.NATURE REVIEWS MATERIALS(11),847.
MLA Tang, ZM,et al."A materials-science perspective on tackling COVID-19".NATURE REVIEWS MATERIALS .11(2020):847.
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