KMS Shanghai Institute of Ceramics，Chinese Academy of Sciences
| Biocompatibility of borosilicate glass-ceramics based LTCC materials for microfluidic biosensor application | |
| Liang, Yongyuan; Ma, Mingsheng; Qian, Suxiang; Zhuang, Hui; Li, Kunqiang; Liu, Zhifu; Li, Yongxiang | |
| 2019-12-31 | |
| Source Publication | INTERNATIONAL JOURNAL OF APPLIED CERAMIC TECHNOLOGY
 |
| ISSN | 1546-542X |
| Subtype | Article; Early Access |
| Abstract | Three kinds of borosilicate glass-ceramics Low temperature co-fired ceramics (LTCC) substrate materials, Ca-B-Si-O (CBS), Ca-Al-B-Si-O (CABS), and Ca-Mg-B-Si-O (CMBS), have been prepared, and the biocompatibility of these materials was evaluated. Compared with CBS and CMBS samples, the CABS sample presented the lowest crystallinity and dissolution in the bioleaching experiments. The direct and indirect cell culturing results showed that the CABS sample also possessed the best biocompatibility to the bone mesenchymal stem cells (BMSCs) due to its good bio-stability and surface micro-pore structure. The effects of surface topography and released ions on cytocompatibility were analyzed. These results were expected to offer some guideline information for developing LTCC substrate materials used in the microfluidic biosensors for the future biological and medical application. |
| Keyword | borosilicate glass dielectric materials properties glass-ceramics |
| DOI | 10.1111/ijac.13357 |
| WOS Keyword | IN-VITRO BIOACTIVITY ; COMPOSITE ; SCAFFOLDS |
| Language | 英语 |
| WOS Research Area | Materials Science |
| Publisher | WILEY |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.sic.ac.cn/handle/331005/27545 |
| Collection | 中国科学院上海硅酸盐研究所 |
| Recommended Citation GB/T 7714 | Liang, Yongyuan,Ma, Mingsheng,Qian, Suxiang,et al. Biocompatibility of borosilicate glass-ceramics based LTCC materials for microfluidic biosensor application[J]. INTERNATIONAL JOURNAL OF APPLIED CERAMIC TECHNOLOGY,2019. |
| APA | Liang, Yongyuan.,Ma, Mingsheng.,Qian, Suxiang.,Zhuang, Hui.,Li, Kunqiang.,...&Li, Yongxiang.(2019).Biocompatibility of borosilicate glass-ceramics based LTCC materials for microfluidic biosensor application.INTERNATIONAL JOURNAL OF APPLIED CERAMIC TECHNOLOGY. |
| MLA | Liang, Yongyuan,et al."Biocompatibility of borosilicate glass-ceramics based LTCC materials for microfluidic biosensor application".INTERNATIONAL JOURNAL OF APPLIED CERAMIC TECHNOLOGY (2019). |
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