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Sr- and Si-containing bioceramic stimulate in vitro osteogenesis
Lin, Chucheng; Zhu, Huiying; Zeng, Yi
2019-05-15
Source PublicationSURFACE & COATINGS TECHNOLOGY
ISSN0257-8972
Volume365Pages:129
SubtypeArticle; Proceedings Paper
AbstractTo develop composite bioactive bioceramics for bone tissue engineering, Sr-5(PO4)(2)SiO4 (SrPS) bioceramics that containing bioactive Si and Sr ions were successfully prepared by compression molding in the present study. Cell proliferation and molecular biology actions were studied using the rabbit bone marrow stromal cells (rBMSCs) to evaluate the biological properties of this novel bioceramic. The results showed that comparing with traditional beta-tricalcium phosphate (beta-TCP), the prepared SrPS bioceramics presented satisfied cytocompatibility and enhanced cell proliferation. In addition, the expression of the bone-related gene bone morphorgenetic protein 2 (BMP2) and osteocalcin (OCN) of rBMSCs was also improved. These results demonstrated that the prepared SrPS bioceramics could stimulate osteogenic in vitro, demonstrating that they might have bright potential for being used as bone repair material.
KeywordSr-5(PO4)(2)SiO4 bioceramic Cytocompatibility Gene expression Osteogenesis
DOI10.1016/j.surfcoat.2018.10.063
Language英语
WOS Research AreaMaterials Science ; Physics
PublisherELSEVIER SCIENCE SA
Citation statistics
Cited Times:1[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.sic.ac.cn/handle/331005/27113
Collection中国科学院上海硅酸盐研究所
Recommended Citation
GB/T 7714
Lin, Chucheng,Zhu, Huiying,Zeng, Yi. Sr- and Si-containing bioceramic stimulate in vitro osteogenesis[J]. SURFACE & COATINGS TECHNOLOGY,2019,365:129.
APA Lin, Chucheng,Zhu, Huiying,&Zeng, Yi.(2019).Sr- and Si-containing bioceramic stimulate in vitro osteogenesis.SURFACE & COATINGS TECHNOLOGY,365,129.
MLA Lin, Chucheng,et al."Sr- and Si-containing bioceramic stimulate in vitro osteogenesis".SURFACE & COATINGS TECHNOLOGY 365(2019):129.
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