Corrosion Motivated ROS Generation Helps Endow Titanium with Broad-Spectrum Antibacterial Abilities

doi:10.1002/admi.201900514

SIC OpenIR

	Corrosion Motivated ROS Generation Helps Endow Titanium with Broad-Spectrum Antibacterial Abilities
	Wang, Donghui; Li, Qianwen; Qiu, Jiajun; Zhang, Xianming; Ge, Naijian; Liu, Xuanyong
	2019-09-06
Source Publication	ADVANCED MATERIALS INTERFACES
ISSN	2196-7350
Volume	6 Issue:17
Subtype	Article
Abstract	Materials that spontaneously generate reactive oxygen species (ROS) possess various industrial applications, such as organocatalysis, wastewater, and waste gas government. Given that bacteria, especially the more resistant Gram-negative (Gram-) species, are sensitive to ROS, endowing biomaterials with ROS producing abilities may be a useful strategy to fight against bacteria. Herein a minocycline-loaded Mg-Fe layered double hydroxides film is constructed on the surface of biomedical titanium. The prepared films possess excellent ROS generating capabilities driven by the corrosion process of titanium, which can continuously release hydroxyl radicals without external stimuli. Both Gram-positive (Gram+) Staphylococcus aureus and (Gram-) Escherichia coli cells can be killed by the constructed platform under the synergistic effect of the released minocycline and ROS. Besides, the in vitro cell culture assay reveals good cytocompatibility of the as-prepared films.
Keyword	antibacterial corrosion Mg-Fe layered double hydroxides minocycline ROS
DOI	10.1002/admi.201900514
Language	英语
WOS Research Area	Chemistry ; Materials Science
Publisher	WILEY
Citation statistics	Cited Times:5[WOS] [WOS Record] [Related Records in WOS]
Document Type	期刊论文
Identifier	http://ir.sic.ac.cn/handle/331005/26991
Collection	中国科学院上海硅酸盐研究所
Recommended Citation GB/T 7714	Wang, Donghui,Li, Qianwen,Qiu, Jiajun,et al. Corrosion Motivated ROS Generation Helps Endow Titanium with Broad-Spectrum Antibacterial Abilities[J]. ADVANCED MATERIALS INTERFACES,2019,6(17).
APA	Wang, Donghui,Li, Qianwen,Qiu, Jiajun,Zhang, Xianming,Ge, Naijian,&Liu, Xuanyong.(2019).Corrosion Motivated ROS Generation Helps Endow Titanium with Broad-Spectrum Antibacterial Abilities.ADVANCED MATERIALS INTERFACES,6(17).
MLA	Wang, Donghui,et al."Corrosion Motivated ROS Generation Helps Endow Titanium with Broad-Spectrum Antibacterial Abilities".ADVANCED MATERIALS INTERFACES 6.17(2019).

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