SIC OpenIR
Construction of Silica-Based Micro/Nanoplatforms for Ultrasound Theranostic Biomedicine
Zhou, Yang; Han, Xiaoxia2,3; Jing, Xiangxiang1; Chen, Yu4
2017
发表期刊ADVANCED HEALTHCARE MATERIALS
ISSN2192-2640
卷号6期号:18
摘要Ultrasound (US)-based biomedicine has been extensively explored for its applications in both diagnostic imaging and disease therapy. The fast development of theranostic nanomedicine significantly promotes the development of US-based biomedicine. This progress report summarizes and discusses the recent developments of rational design and fabrication of silica-based micro/nanoparticles for versatile US-based biomedical applications. The synthetic strategies and surface-engineering approaches of silica-based micro/nanoparticles are initially discussed, followed by detailed introduction on their US-based theranostic applications. They have been extensively explored in contrast-enhanced US imaging, US-based multi-modality imaging, synergistic high-intensity focused US (HIFU) ablation, sonosensitizer-enhanced sonodynamic therapy (SDT), as well as US-triggered chemotherapy. Their biological effects and biosafety have been briefly discussed to guarantee further clinical translation. Based on the high biocompatibility, versatile composition/structure and high performance in US-based theranostic biomedicine, these silica-based theranostic agents are expected to pave a new way for achieving efficient US-based theranostics of disease by taking the specific advantages of material science, nanotechnology and US-based biomedicine.
DOI10.1002/adhm.201700646
WOS记录号WOS:000411265400012
EI入藏号2192-2659
引用统计
文献类型期刊论文
条目标识符http://ir.sic.ac.cn/handle/331005/26644
专题中国科学院上海硅酸盐研究所
作者单位1.Southwest Jiaotong Univ, Affiliated Hosp, Peoples Hosp Chengdu City 3, Dept Ultrasound, Chengdu 600031, Sichuan, Peoples R China
2.Hainan Gen Hosp, Dept Ultrasound, Haikou 570311, Hainan, Peoples R China
3.Chongqing Med Univ, Affiliated Hosp 2, Inst Ultrasound Imaging, Chongqing 400010, Peoples R China
4.Chongqing Med Univ, Affiliated Hosp 2, Dept Ultrasound, Chongqing 400010, Peoples R China
5.Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, Shanghai 200050, Peoples R China
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GB/T 7714
Zhou, Yang,Han, Xiaoxia,Jing, Xiangxiang,et al. Construction of Silica-Based Micro/Nanoplatforms for Ultrasound Theranostic Biomedicine[J]. ADVANCED HEALTHCARE MATERIALS,2017,6(18).
APA Zhou, Yang,Han, Xiaoxia,Jing, Xiangxiang,&Chen, Yu.(2017).Construction of Silica-Based Micro/Nanoplatforms for Ultrasound Theranostic Biomedicine.ADVANCED HEALTHCARE MATERIALS,6(18).
MLA Zhou, Yang,et al."Construction of Silica-Based Micro/Nanoplatforms for Ultrasound Theranostic Biomedicine".ADVANCED HEALTHCARE MATERIALS 6.18(2017).
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