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Ultralong Hydroxyapatite Nanowire/Collagen Biopaper with High Flexibility, Improved Mechanical Properties and Excellent Cellular Attachment
Sun, Tuan-Wei1,2; Zhu, Ying-Jie1,2; Chen, Feng1; Zhang, Yong-Gang1,2
2017
发表期刊Chemistry - An Asian Journal
ISSN18614728
卷号12期号:6页码:655-664
摘要Highly flexible hydroxyapatite/collagen (HAP/Col) composite membranes are regarded to be significant for guided bone regeneration application owing to their similar chemical composition to that of natural bone, excellent bioactivity and good osteoconductivity. However, the mechanical strength of the HAP/Col composite membranes is usually weak, which leads to difficult surgical operations and low mechanical stability during the bone healing process. Herein, highly flexible ultralong hydroxyapatite nanowires/collagen (UHANWs/Col) composite biopaper sheets with weight fractions of UHANWs ranging from 0 to 100 % are facilely synthesized. The UHANWs are able to weave with each other to construct a three-dimensional fabric structure in the collagen matrix, providing a strong interaction between UHANWs and an intermolecular force between UHANWs and the collagen matrix. The as-prepared UHANWs/Col composite biopaper exhibits improved mechanical properties and high flexibility. More importantly, the as-prepared highly flexible 70 wt % UHANWs/Col composite biopaper exhibits an excellent cytocompatibility and outstanding cellular attachment performance as compared with the pure collagen and 70 wt % HAP nanorods/Col membranes. In consideration of its superior mechanical properties and outstanding cellular attachment performance, the as-prepared UHANWs/Col composite biopaper is promising for applications in various biomedical fields such as guided bone regeneration. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
DOI10.1002/asia.201601592
EI入藏号20170903385299
EI主题词Composite membranes
EI分类号461.2 Biological Materials and Tissue Engineering - 461.6 Medicine and Pharmacology - 462.5 Biomaterials (including synthetics) - 761 Nanotechnology - 801.4 Physical Chemistry - 804.2 Inorganic Compounds - 933 Solid State Physics - 951 Materials Science
引用统计
被引频次:9[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.sic.ac.cn/handle/331005/25725
专题中国科学院上海硅酸盐研究所
作者单位1.State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai; 200050, China;
2.University of Chinese Academy of Sciences, Beijing; 100049, China
推荐引用方式
GB/T 7714
Sun, Tuan-Wei,Zhu, Ying-Jie,Chen, Feng,et al. Ultralong Hydroxyapatite Nanowire/Collagen Biopaper with High Flexibility, Improved Mechanical Properties and Excellent Cellular Attachment[J]. Chemistry - An Asian Journal,2017,12(6):655-664.
APA Sun, Tuan-Wei,Zhu, Ying-Jie,Chen, Feng,&Zhang, Yong-Gang.(2017).Ultralong Hydroxyapatite Nanowire/Collagen Biopaper with High Flexibility, Improved Mechanical Properties and Excellent Cellular Attachment.Chemistry - An Asian Journal,12(6),655-664.
MLA Sun, Tuan-Wei,et al."Ultralong Hydroxyapatite Nanowire/Collagen Biopaper with High Flexibility, Improved Mechanical Properties and Excellent Cellular Attachment".Chemistry - An Asian Journal 12.6(2017):655-664.
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