SIC OpenIR
Symmetry-breaking assembled porous calcite microspheres and their multiple dental applications
Ma, Ming1; Yan, Yanhong2; Qi, Chao1; Qi, Shengcai3; Chern, Shixiong1; Shang, Guangwei3; Wang, Raorao3; Chen, Hangrong1
2017
发表期刊Science China Materials
ISSN20958226
卷号60期号:6页码:516-528
摘要Biomedical applications of porous calcium carbonate (CaCO3) microspheres have been mainly restricted by their aqueous instability and low remineralization rate. To overcome these obstacles, a novel symmetry-breaking assembled porous calcite microsphere (PCMS) was constructed in an ethanol/water mixed system using a two-step vapor-diffusion/aging crystallization strategy. In contrast to the conventional additive-induced crystallization method, the present strategy was performed under mild conditions and was free from any foreign additives, thus avoiding the potential contamination of the final product. Meanwhile, the prepared PCMSs were characterized by their highly uniform spherical morphology and large open pores, which are favorable for large protein delivery. An antimicrobial study of immunoglobulin Y (IgY)-loaded PCMSs revealed excellent antimicrobial activity against Streptococcus mutans. More importantly, they showed surprisingly rapid transformation to bone minerals in physiological medium. Evaluation of the in vitro efficacy of PCMSs in dentinal tubule occlusion demonstrated their powerful potential to serve as a catalyst in the repair of dental hard tissue. Therefore, the developed PCMSs show great promise as multifunctional biomaterials for dental treatment applications. © 2017, Science China Press and Springer-Verlag GmbH Germany.
DOI10.1007/s40843-017-9038-5
EI入藏号20174804475654
EI主题词Microspheres
EI分类号461.9 Biology - 803 Chemical Agents and Basic Industrial Chemicals - 804 Chemical Products Generally
引用统计
文献类型期刊论文
条目标识符http://ir.sic.ac.cn/handle/331005/25618
专题中国科学院上海硅酸盐研究所
作者单位1.State Key Lab of High Performance Ceramics and Superfine Microstructures, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai; 200050, China;
2.Shanghai Engineering Research Center of Tooth Restoration and Regeneration, Department of Pediatric Dentistry, School of Stomatology, Tongji University, Shanghai; 200072, China;
3.Department of Stomatology, Shanghai Tenth People’s Hospital, Tongji University, Shanghai; 200072, China
推荐引用方式
GB/T 7714
Ma, Ming,Yan, Yanhong,Qi, Chao,et al. Symmetry-breaking assembled porous calcite microspheres and their multiple dental applications[J]. Science China Materials,2017,60(6):516-528.
APA Ma, Ming.,Yan, Yanhong.,Qi, Chao.,Qi, Shengcai.,Chern, Shixiong.,...&Chen, Hangrong.(2017).Symmetry-breaking assembled porous calcite microspheres and their multiple dental applications.Science China Materials,60(6),516-528.
MLA Ma, Ming,et al."Symmetry-breaking assembled porous calcite microspheres and their multiple dental applications".Science China Materials 60.6(2017):516-528.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Ma, Ming]的文章
[Yan, Yanhong]的文章
[Qi, Chao]的文章
百度学术
百度学术中相似的文章
[Ma, Ming]的文章
[Yan, Yanhong]的文章
[Qi, Chao]的文章
必应学术
必应学术中相似的文章
[Ma, Ming]的文章
[Yan, Yanhong]的文章
[Qi, Chao]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。