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Mn-containing titanium surface with favorable osteogenic and antimicrobial functions synthesized by PIII&D
Yu, Le; Tian, Yaxin; Qiao, Yuqin; Liu, Xuanyong
2017
Source PublicationColloids and Surfaces B: Biointerfaces
ISSN09277765
Volume152Pages:376-384
AbstractReasonable incorporation of manganese into titanium is believed to be able to enhance the osteogenic and antibacterial activities of orthopedic implants. However, it is still a challenge to compromise Mn-induced cytotoxicity and better develop its biocompatibility and antimicrobial ability. To pinpoint this issue, a stable Mn ion release platform was created on Ti using plasma immersion ion implantation and deposition (PIII&D) technique. Compared with as-etched titanium, as a result, promoted antibacterial abilities against gram-negative bacteria species and enhanced osteogenic-related gene expressions on rBMMSC were observed on Mn-containing sample. Meanwhile, the Mn-containing samples showed no obvious cytotoxicity. Our results here provide insight to be better understanding the relationships between additives-induced biological performance and the dose, state, and stability of the doped element. © 2017
DOI10.1016/j.colsurfb.2017.01.047
EI Accession Number20170503309277
EI KeywordsGene expression
EI Classification Number461.9 Biology - 461.9.1 Immunology - 542.3 Titanium and Alloys - 543.2 Manganese and Alloys - 932.3 Plasma Physics
Citation statistics
Cited Times:7[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.sic.ac.cn/handle/331005/25593
Collection中国科学院上海硅酸盐研究所
AffiliationState Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai; 200050, China
Recommended Citation
GB/T 7714
Yu, Le,Tian, Yaxin,Qiao, Yuqin,et al. Mn-containing titanium surface with favorable osteogenic and antimicrobial functions synthesized by PIII&D[J]. Colloids and Surfaces B: Biointerfaces,2017,152:376-384.
APA Yu, Le,Tian, Yaxin,Qiao, Yuqin,&Liu, Xuanyong.(2017).Mn-containing titanium surface with favorable osteogenic and antimicrobial functions synthesized by PIII&D.Colloids and Surfaces B: Biointerfaces,152,376-384.
MLA Yu, Le,et al."Mn-containing titanium surface with favorable osteogenic and antimicrobial functions synthesized by PIII&D".Colloids and Surfaces B: Biointerfaces 152(2017):376-384.
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