SIC OpenIR
Two-Dimensional Tantalum Carbide (MXenes) Composite Nanosheets for Multiple Imaging-Guided Photothermal Tumor Ablation
Dai, Chen1; Chen, Yu3; Jing, Xiangxiang2; Xiang, Lihua1; Yang, Dayang2; Lin, Han3; Liu, Zhuang4; Han, Xiaoxia5; Wu, Rong1
2017
发表期刊ACS Nano
ISSN19360851
卷号11期号:12页码:12696-12712
摘要MXenes, an emerging family of graphene-analogues two-dimensional (2D) materials, have attracted continuous and tremendous attention in many application fields because of their intrinsic physiochemical properties and high performance in versatile applications. In this work, we report on the construction of tantalum carbide (Ta4C3) MXene-based composite nanosheets for multiple imaging-guided photothermal tumor ablation, which has been achieved by rational choice of the composition of MXenes and their surface functionalization. A redox reaction was activated on the surface of tantalum carbide (Ta4C3) MXene for in situ growth of manganese oxide nanoparticles (MnOx/Ta4C3) based on the reducing surface of the nanosheets. The tantalum components of MnOx/Ta4C3acted as the high-performance contrast agents for contrast-enhanced computed tomography, and the integrated MnOxcomponent functionalized as the tumor microenvironment-responsive contrast agents for T1-weighted magnetic resonance imaging. The photothermal-conversion performance of MnOx/Ta4C3composite nanosheets not only has achieved contrast-enhanced photoacoustic imaging, but also realized the significant tumor-growth suppression by photothermal hyperthermia. This work broadens the biomedical applications of MXenes, not only by the fabrication of family members of biocompatible MXenes, but also by the development of functionalization strategies of MXenes for cancer-theranostic applications. © 2017 American Chemical Society.
DOI10.1021/acsnano.7b07241
EI入藏号20180204627948
EI主题词Tantalum compounds
EI分类号461.2 Biological Materials and Tissue Engineering - 461.9.1 Immunology - 641.2 Heat Transfer - 723.5 Computer Applications - 746 Imaging Techniques - 761 Nanotechnology - 802.2 Chemical Reactions - 804 Chemical Products Generally - 804.2 Inorganic Compounds - 933 Solid State Physics
引用统计
被引频次:21[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.sic.ac.cn/handle/331005/25527
专题中国科学院上海硅酸盐研究所
作者单位1.Department of Ultrasound in Medicine, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai; 200072, China;
2.Department of Ultrasound, Hainan General Hospital, Haikou; 570311, China;
3.State Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai; 200050, China;
4.Department of Radiology, Fudan University Shanghai Cancer Center, Shanghai; 200032, China;
5.Second Affiliated Hospital, Institute of Ultrasound Imaging, Chongqing Medical University, Chongqing; 400010, China
推荐引用方式
GB/T 7714
Dai, Chen,Chen, Yu,Jing, Xiangxiang,et al. Two-Dimensional Tantalum Carbide (MXenes) Composite Nanosheets for Multiple Imaging-Guided Photothermal Tumor Ablation[J]. ACS Nano,2017,11(12):12696-12712.
APA Dai, Chen.,Chen, Yu.,Jing, Xiangxiang.,Xiang, Lihua.,Yang, Dayang.,...&Wu, Rong.(2017).Two-Dimensional Tantalum Carbide (MXenes) Composite Nanosheets for Multiple Imaging-Guided Photothermal Tumor Ablation.ACS Nano,11(12),12696-12712.
MLA Dai, Chen,et al."Two-Dimensional Tantalum Carbide (MXenes) Composite Nanosheets for Multiple Imaging-Guided Photothermal Tumor Ablation".ACS Nano 11.12(2017):12696-12712.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Dai, Chen]的文章
[Chen, Yu]的文章
[Jing, Xiangxiang]的文章
百度学术
百度学术中相似的文章
[Dai, Chen]的文章
[Chen, Yu]的文章
[Jing, Xiangxiang]的文章
必应学术
必应学术中相似的文章
[Dai, Chen]的文章
[Chen, Yu]的文章
[Jing, Xiangxiang]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。